Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

<p>Abstract</p> <p>Background</p> <p>There is a pressing need to identify novel pathophysiological pathways relevant to depression that can help to reveal targets for the development of new medications. Toll-like receptor 4 (TLR-4) has a regulatory role in the brain...

Full description

Bibliographic Details
Main Authors: Madrigal José LM, García-Bueno Borja, Gárate Iciar, Bravo Lidia, Berrocoso Esther, Caso Javier R, Micó Juan A, Leza Juan C
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Neuroinflammation
Subjects:
neuroinflammation
chronic mild stress
depression
innate immunity
TLR-4
LPS
Online Access:http://www.jneuroinflammation.com/content/8/1/151

Internet

http://www.jneuroinflammation.com/content/8/1/151

Similar Items