Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity

WW domain tandem-containing proteins such as KIBRA, YAP, and MAGI play critical roles in cell growth and polarity via binding to and positioning target proteins in specific subcellular regions. An immense disparity exists between promiscuity of WW domain-mediated target bindings and specific roles o...

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Bibliographic Details
Main Authors: Zhijie Lin, Zhou Yang, Ruiling Xie, Zeyang Ji, Kunliang Guan, Mingjie Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
YAP
Online Access:https://elifesciences.org/articles/49439