Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies

Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies

Allergic (Th2high immunophenotype) asthmatics have a heightened susceptibility to common respiratory viral infections such as human rhinovirus. Evidence suggests that the innate interferon response is deficient in asthmatic/atopic individuals, while other studies show no differences in antiviral res...

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Bibliographic Details
Main Authors: Jean-François Lauzon-Joset, Anya C. Jones, Kyle T. Mincham, Jenny A. Thomas, Louis A. Rosenthal, Anthony Bosco, Patrick G. Holt, Deborah H. Strickland
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
rhinovirus
Th2-atopy
type I interferon
allergic asthma
microarray
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01805/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01805/full

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