Regression of Human Prostate Tumors and Metastases in Nude Mice following Treatment with the Recombinant Oncolytic Vaccinia Virus GLV-1h68

Virotherapy using oncolytic vaccinia virus strains is one of the most promising new strategies for cancer therapy. In the current study, we analyzed the therapeutic efficacy of the oncolytic vaccinia virus GLV-1h68 against two human prostate cancer cell lines DU-145 and PC-3 in cell culture and in t...

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Main Authors: Ivaylo Gentschev, Ulrike Donat, Elisabeth Hofmann, Stephanie Weibel, Marion Adelfinger, Viktoria Raab, Martin Heisig, Nanhai Chen, Yong A. Yu, Jochen Stritzker, Aladar A. Szalay
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/489759