Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio.

Many eukaryotic developmental and cell fate decisions that are effected post-transcriptionally involve RNA binding proteins as regulators of translation of key mRNAs. In malaria parasites (Plasmodium spp.), the development of round, non-motile and replicating exo-erythrocytic liver stage forms from...

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Main Authors: Carina S S Gomes-Santos, Joanna Braks, Miguel Prudêncio, Céline Carret, Ana Rita Gomes, Arnab Pain, Theresa Feltwell, Shahid Khan, Andrew Waters, Chris Janse, Gunnar R Mair, Maria M Mota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625527/pdf/?tool=EBI