Nuclear legumain activity in colorectal cancer.

The cysteine protease legumain is involved in several biological and pathological processes, and the protease has been found over-expressed and associated with an invasive and metastatic phenotype in a number of solid tumors. Consequently, legumain has been proposed as a prognostic marker for certai...

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Bibliographic Details
Main Authors: Mads H Haugen, Harald T Johansen, Solveig J Pettersen, Rigmor Solberg, Klaudia Brix, Kjersti Flatmark, Gunhild M Maelandsmo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542341?pdf=render