Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity.

The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. Bordetella bronchiseptica and B. pertussis stimulate robust TLR4 responses that are required to control the i...

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Bibliographic Details
Main Authors: Daniel N Wolfe, Anne M Buboltz, Eric T Harvill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2627931?pdf=render