TP53inp1 Gene Is Implicated in Early Radiation Response in Human Fibroblast Cells

TP53inp1 Gene Is Implicated in Early Radiation Response in Human Fibroblast Cells

Tumor protein 53-induced nuclear protein-1 (TP53inp1) is expressed by activation via p53 and p73. The purpose of our study was to investigate the role of TP53inp1 in response of fibroblasts to ionizing radiation. γ-Ray radiation dose-dependently induces the expression of TP53inp1 in human immortaliz...

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Bibliographic Details
Main Authors: Nikolett Sándor, Boglárka Schilling-Tóth, Enikő Kis, Lili Fodor, Fruzsina Mucsányi, Géza Sáfrány, Hargita Hegyesi
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
TP53inp1
p53-network
autophagy
senescence
radiosensitivity
RNA interference
GDF-15
CDKN1A
Online Access:http://www.mdpi.com/1422-0067/16/10/25450

Internet

http://www.mdpi.com/1422-0067/16/10/25450

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