A comparative bioinformatic analysis of C9orf72

C9orf72 is associated with frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS), both of which are devastating neurodegenerative diseases. Findings suggest that an expanded hexanucleotide repeat in the non-coding region of the C9orf72 gene is the most common cause of familial FTD an...

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Bibliographic Details
Main Authors: Shalini Iyer, K. Ravi Acharya, Vasanta Subramanian
Format: Article
Language:English
Published: PeerJ Inc. 2018-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4391.pdf