Elevated Levels of NLRP3 in Cerebrospinal Fluid of Patients With Autoimmune GFAP Astrocytopathy

Elevated Levels of NLRP3 in Cerebrospinal Fluid of Patients With Autoimmune GFAP Astrocytopathy

Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy, a newly defined autoimmune encephalitis, is an antibody-mediated meningoencephalomyelitis. The pathogenesis of the disease is still unclear. Nod-like receptor protein 3 (NLRP3) inflammasome is a complex composed of a variety of protei...

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Bibliographic Details
Main Authors: Ying Luo, Wei Yan, Zheyi Zhou, Baozhu Liu, Zhanhang Wang, Jinyu Chen, Honghao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neurology
Subjects:
autoimmune GFAP astrocytopathy
neuroinflammation
EDSS score
NLRP3 inflammasome
inflammatory cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01019/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01019/full

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