Effect of 0.25 ppm Ozone exposure on pulmonary damage induced by bleomycin

To study the effect of ozone in a chronically damaged lung, we used a bleomycin (BLM) induced pulmonary fibrosis model. Both endotracheal instillation of BLM and O3 exposure both produce lung inflammation and fibrosis. Oxidative stress would be a common mechanism of damage for both BLM and O3. Our a...

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Bibliographic Details
Main Authors: MANUEL OYARZÚN, NELSON DUSSAUBAT, SERGIO GONZÁLEZ
Format: Article
Language:English
Published: BMC 2005-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400007