ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins

ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins

The endosomal sorting complexes required for transport (ESCRT) machinery mediates the physical separation between daughter cells during cytokinetic abscission. This process is regulated by the abscission checkpoint, a genome protection mechanism that relies on Aurora B and the ESCRT-III subunit CHMP...

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Bibliographic Details
Main Authors: Anna Caballe, Dawn M Wenzel, Monica Agromayor, Steven L Alam, Jack J Skalicky, Magdalena Kloc, Jeremy G Carlton, Leticia Labrador, Wesley I Sundquist, Juan Martin-Serrano
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
cytokinesis
abscission checkpoint
ESCRT
ULK3
phosphorylation
Online Access:https://elifesciences.org/articles/06547

Internet

https://elifesciences.org/articles/06547

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