Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)
Abstract Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms of pathogenesis but also in terms of...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Acta Neuropathologica Communications |
Online Access: | http://link.springer.com/article/10.1186/s40478-018-0511-7 |