Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control
<p>Abstract</p> <p>Background</p> <p>We have previously constructed a doxycycline (dox)-dependent HIV-1 variant by incorporating the Tet-On gene regulatory system into the viral genome. Replication of this HIV-rtTA virus is driven by the dox-inducible transactivator pro...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-11-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/3/1/82 |