JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding

JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding

Summary: The liver is a key regulator of systemic energy homeostasis whose proper function is dependent on the circadian clock. Here, we show that livers deficient in the oscillator component JARID1a exhibit a dysregulation of genes involved in energy metabolism. Importantly, we find that mice that...

Full description

Bibliographic Details
Main Authors: Kacee Ann DiTacchio, Diana Kalinowska, Anand Rajamani Saran, Ashley Byrne, Christopher Vollmers, Luciano DiTacchio
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports
Subjects:
circadian
metabolism
JARID1a
refeeding
fasting
lipid
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720306215

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720306215

Similar Items