JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding
Summary: The liver is a key regulator of systemic energy homeostasis whose proper function is dependent on the circadian clock. Here, we show that livers deficient in the oscillator component JARID1a exhibit a dysregulation of genes involved in energy metabolism. Importantly, we find that mice that...
Main Authors: | Kacee Ann DiTacchio, Diana Kalinowska, Anand Rajamani Saran, Ashley Byrne, Christopher Vollmers, Luciano DiTacchio |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124720306215 |
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