Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection.

Tissue-specific B-cell dysfunction and generalized memory B-cell loss during acute SIV infection.

BACKGROUND:Primary HIV-infected patients display severe and irreversible damage to different blood B-cell subsets which is not restored by highly efficient anti-retroviral therapy (HAART). Because longitudinal investigations of primary HIV-infection is limited by the availability of lymphoid organs,...

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Bibliographic Details
Main Authors: Sandrine Peruchon, Nada Chaoul, Chantal Burelout, Benoit Delache, Patricia Brochard, Pascale Laurent, Fabrice Cognasse, Sophie Prévot, Olivier Garraud, Roger Le Grand, Yolande Richard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2695011?pdf=render

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http://europepmc.org/articles/PMC2695011?pdf=render

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