Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury

Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury

Trauma or neurodegenerative diseases trigger the retrograde death of retinal ganglion cells (RGCs), causing an irreversible functional loss. AT-rich interaction domain 1A (ARID1A), a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex, has been shown to play crucial...

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Bibliographic Details
Main Authors: Xue-Qi Peng, Shang-Kun Dai, Chang-Ping Li, Pei-Pei Liu, Zhi-Meng Wang, Hong-Zhen Du, Zhao-Qian Teng, Shu-Guang Yang, Chang-Mei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Arid1a
SWI/SNF
retinal ganglion cell
optic nerve crush
survival
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00131/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00131/full

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