Condensins are Required for Maintenance of Nuclear Architecture

The 3-dimensional spatial organization of eukaryotic genomes is important for regulation of gene expression as well as DNA damage repair. It has been proposed that one basic biophysical property of all nuclei is that interphase chromatin must be kept in a condensed prestressed state in order to prev...

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Bibliographic Details
Main Authors: Carolyn M. George, Julianna Bozler, Huy Q. Nguyen, Giovanni Bosco
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/3/3/865