Condensins are Required for Maintenance of Nuclear Architecture
The 3-dimensional spatial organization of eukaryotic genomes is important for regulation of gene expression as well as DNA damage repair. It has been proposed that one basic biophysical property of all nuclei is that interphase chromatin must be kept in a condensed prestressed state in order to prev...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-08-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/3/3/865 |