Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid

Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid

Tropodithietic acid (TDA) is a structurally unique sulfur-containing antibiotic from the Roseobacter clade bacterium Phaeobacter inhibens DSM 17395 and a few other related species. We have synthesised several structural analogues of TDA and used them in bioactivity tests against Staphylococcus aureu...

Full description

Bibliographic Details
Main Authors: Patrick Rabe, Tim A. Klapschinski, Nelson L. Brock, Christian A. Citron, Paul D’Alvise, Lone Gram, Jeroen S. Dickschat
Format: Article
Language:English
Published: Beilstein-Institut 2014-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antibiotics
natural products
Roseobacter
SAR study
tropodithietic acid
tropone
Online Access:https://doi.org/10.3762/bjoc.10.188

Internet

https://doi.org/10.3762/bjoc.10.188

Similar Items