New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target?

New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target?

Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder characterized by upper and lower motor neuron degeneration, which leads to progressive paralysis of skeletal muscles and, ultimately, respiratory failure between 2–5 years after symptom onset. Unfortunately, currently accepted treat...

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Bibliographic Details
Main Authors: Carlos Gonzalez-Fernandez, Pau González, Francisco Javier Rodríguez
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
als; astrocytes; frizzled; human; microglia; motor neuron; neurodegeneration; neuroinflammation; spinal cord; wnt
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=9;spage=1580;epage=1589;aulast=Gonzalez-Fernandez

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=9;spage=1580;epage=1589;aulast=Gonzalez-Fernandez

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