Improved Oral Bioavailability Using a Solid Self-Microemulsifying Drug Delivery System Containing a Multicomponent Mixture Extracted from Salvia miltiorrhiza

Improved Oral Bioavailability Using a Solid Self-Microemulsifying Drug Delivery System Containing a Multicomponent Mixture Extracted from Salvia miltiorrhiza

The active ingredients of salvia (dried root of Salvia miltiorrhiza) include both lipophilic (e.g., tanshinone IIA, tanshinone I, cryptotanshinone and dihydrotanshinone I) and hydrophilic (e.g., danshensu and salvianolic acid B) constituents. The low oral bioavailability of these constituents may li...

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Bibliographic Details
Main Authors: Xiaolin Bi, Xuan Liu, Liuqing Di, Qiang Zu
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Molecules
Subjects:
solid self-microemulsifying drug delivery system
salvia extract
dissolution rate
bioavailability
oral drug delivery
Online Access:http://www.mdpi.com/1420-3049/21/4/456

Internet

http://www.mdpi.com/1420-3049/21/4/456

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