Distinct Features of Canine Non-conventional CD4−CD8α− Double-Negative TCRαβ+ vs. TCRγδ+ T Cells

Distinct Features of Canine Non-conventional CD4−CD8α− Double-Negative TCRαβ+ vs. TCRγδ+ T Cells

The role of conventional TCRαβ+CD4+ or TCRαβ+CD8α+ single-positive (sp) T lymphocytes in adaptive immunity is well-recognized. However, non-conventional T cells expressing TCRαβ or TCRγδ but lacking CD4 and CD8α expression [i.e., CD4−CD8α− double-negative (dn) T cells] are thought to play a role at...

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Bibliographic Details
Main Authors: Friederike V. Rabiger, Kathrin Rothe, Heiner von Buttlar, Doris Bismarck, Mathias Büttner, Peter F. Moore, Maria Eschke, Gottfried Alber
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
dog
canine T cells
CD4−CD8α−
double-negative
non-conventional T cells
TCRαβ
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02748/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02748/full

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