FASTmC: A Suite of Predictive Models for Nonreference-Based Estimations of DNA Methylation

FASTmC: A Suite of Predictive Models for Nonreference-Based Estimations of DNA Methylation

We describe a suite of predictive models, coined FASTmC, for nonreference, cost-effective exploration and comparative analysis of context-specific DNA methylation levels. Accurate estimations of true DNA methylation levels can be obtained from as few as several thousand short-reads generated from wh...

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Bibliographic Details
Main Authors: Adam J. Bewick, Brigitte T. Hofmeister, Kevin Lee, Xiaoyu Zhang, David W. Hall, Robert J. Schmitz
Format: Article
Language:English
Published: Oxford University Press 2016-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
epigenetics
DNA methylation
whole-genome bisulfite sequencing
methylome
modeling
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.115.025668

Internet

http://g3journal.org/lookup/doi/10.1534/g3.115.025668

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