MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway

MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway

Abstract Background Cardiomyocyte apoptosis is a common pathological manifestation that occurs in several heart diseases. This study aimed to explore the mechanism of microRNA-486 (miR-486) in cardiomyocyte apoptosis by interfering with the p53-activated BCL-2 associated mitochondrial pathway. Metho...

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Bibliographic Details
Main Authors: Yuhan Sun, Qiang Su, Lang Li, Xiantao Wang, Yuanxi Lu, Jiabao Liang
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Cardiomyocyte
Apoptosis
miR-486
P53
BCL-2 pathway
Online Access:http://link.springer.com/article/10.1186/s12872-017-0549-7

Internet

http://link.springer.com/article/10.1186/s12872-017-0549-7

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