Bioreducible Micelles Self-Assembled from Poly(ethylene glycol)-Cholesteryl Conjugate As a Drug Delivery Platform

Bioreducible Micelles Self-Assembled from Poly(ethylene glycol)-Cholesteryl Conjugate As a Drug Delivery Platform

The ability of polymeric micelles to self-assemble into nanosized particles has created interest in their application as potential anticancer drug delivery systems. A poly(ethylene glycol)-cholesteryl conjugate (Chol-ss-PEG-ss-Chol) connected by cleavable disulfide linkages was synthesized and used...

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Bibliographic Details
Main Authors: Chulsu Baek, Tae-Lin Ha, Eunjoo Kim, Sang Won Jeong, Se Guen Lee, Sung Jun Lee, Hyun-Chul Kim
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Polymers
Subjects:
polymeric micelles
drug delivery system
biocompatible
disulfide-thiol exchange
stimulus-sensitive polymers
Online Access:http://www.mdpi.com/2073-4360/7/11/1511

Internet

http://www.mdpi.com/2073-4360/7/11/1511

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