Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors

Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors

Transferrin (Tf) is an essential serum protein which delivers iron throughout the body via transferrin-receptor (TfR)-mediated uptake and iron release in early endosomes. Currently, there is no robust method to assay the population of iron-bound Tf in intact cells and tissues. Raman hyperspectral im...

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Bibliographic Details
Main Authors: Ting Chean Khoo, Kate Tubbesing, Alena Rudkouskaya, Shilpi Rajoria, Anna Sharikova, Margarida Barroso, Alexander Khmaladze
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
Transferrin
Iron metabolism
Breast cancer
Raman hyperspectral imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308223

Internet

http://www.sciencedirect.com/science/article/pii/S2213231720308223

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