Assessment of the immunogenicity of residual host cell protein impurities of OsrHSA.

Human serum albumin (HSA) is the most abundant protein in human plasma and is widely used at high doses for treating various diseases. Recombinant HSA is an alternative approach to plasma-derived HSA, providing increased safety and an unlimited supply. However, the safety of the residual host cell p...

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Bibliographic Details
Main Authors: Naghmeh Abiri, Jianlei Pang, Jiquan Ou, Bo Shi, Xianghong Wang, Sucai Zhang, Yunxia Sun, Daichang Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5841786?pdf=render