Multifidelity Analysis for Predicting Rare Events in Stochastic Computational Models of Complex Biological Systems

Rare events such as genetic mutations or cell-cell interactions are important contributors to dynamics in complex biological systems, eg, in drug-resistant infections. Computational approaches can help analyze rare events that are difficult to study experimentally. However, analyzing the frequency a...

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Bibliographic Details
Main Author: Elsje Pienaar
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:Biomedical Engineering and Computational Biology
Online Access:https://doi.org/10.1177/1179597218790253