The Mevalonate Pathway Is Indispensable for Adipocyte Survival

Summary: The mevalonate pathway is essential for the synthesis of isoprenoids and cholesterol. Adipose tissue is known as a major site for cholesterol storage; however, the role of the local mevalonate pathway and its synthesized isoprenoids remains unclear. In this study, adipose-specific mevalonat...

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Bibliographic Details
Main Authors: Yu-Sheng Yeh, Huei-Fen Jheng, Mari Iwase, Minji Kim, Shinsuke Mohri, Jungin Kwon, Satoko Kawarasaki, Yongjia Li, Haruya Takahashi, Takeshi Ara, Wataru Nomura, Teruo Kawada, Tsuyoshi Goto
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301780