Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Abstract Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed Tumor Associated Collagen Signatures (T...

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Bibliographic Details
Main Authors: Lucas A. Tomko, Ryan C. Hill, Alexander Barrett, Joseph M. Szulczewski, Matthew W. Conklin, Kevin W. Eliceiri, Patricia J. Keely, Kirk C. Hansen, Suzanne M. Ponik
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-31126-w