Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3

Triple-Negative Breast Cancer: Intact Mismatch Repair and Partial Co-Expression of PD-L1 and LAG-3

Background and AimPoor response to immune checkpoint inhibitors (ICIs) has been observed in most triple-negative breast cancer (TNBC) cases (around 80%). Our aim was to investigate the status of mismatch repair (MMR), microsatellite instability (MSI), programmed death-ligand 1 (PD-L1), and lymphocyt...

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Bibliographic Details
Main Authors: Shafei Wu, Xiaohua Shi, Jing Wang, Xuefei Wang, Yuanyuan Liu, Yufeng Luo, Feng Mao, Xuan Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
CD8
LAG-3
PD-L1
microsatellite instability
triple-negative breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.561793/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.561793/full

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