Lung Cancer Management with Silibinin: A Historical and Translational Perspective

Lung Cancer Management with Silibinin: A Historical and Translational Perspective

The flavonolignan silibinin, the major bioactive component of the silymarin extract of <i>Silybum marianum</i> (milk thistle) seeds, is gaining traction as a novel anti-cancer therapeutic. Here, we review the historical developments that have laid the groundwork for the evaluation of sil...

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Bibliographic Details
Main Authors: Sara Verdura, Elisabet Cuyàs, Verónica Ruiz-Torres, Vicente Micol, Jorge Joven, Joaquim Bosch-Barrera, Javier A. Menendez
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceuticals
Subjects:
silibinin
silymarin
non-small cell lung cancer
EMT
metastasis
STAT3
Online Access:https://www.mdpi.com/1424-8247/14/6/559

Internet

https://www.mdpi.com/1424-8247/14/6/559

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