Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease

Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease

Abstract Imbalance between amyloid-beta (Aβ) peptide synthesis and clearance results in Aβ deregulation. Failure to clear these peptides appears to cause the development of Alzheimer’s disease (AD). In recent years, microRNAs have become established key regulators of biological processes that relate...

Full description

Bibliographic Details
Main Authors: Soheil Madadi, Heidi Schwarzenbach, Massoud Saidijam, Reza Mahjub, Meysam Soleimani
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cell & Bioscience
Subjects:
Ubiquitin–proteasome system
Autophagy
Aβ-degrading proteases
BBB transporters
Phagocytosis
Heat shock proteins
Online Access:http://link.springer.com/article/10.1186/s13578-019-0354-3

Internet

http://link.springer.com/article/10.1186/s13578-019-0354-3

Similar Items