Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells

Anti-VEGF Drugs Influence Epigenetic Regulation and AMD-Specific Molecular Markers in ARPE-19 Cells

Our study assesses the effects of anti-VEGF (Vascular Endothelial Growth Factor) drugs and Trichostatin A (TSA), an inhibitor of histone deacetylase (HDAC) activity, on cultured ARPE-19 (Adult Retinal Pigment Epithelial-19) cells that are immortalized human retinal pigment epithelial cells. ARPE-19...

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Bibliographic Details
Main Authors: Mohamed A. Hamid, M. Tarek Moustafa, Sonali Nashine, Rodrigo Donato Costa, Kevin Schneider, Shari R. Atilano, Baruch D. Kuppermann, M. Cristina Kenney
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
AMD
age-related macular degeneration
trichostatin A (TSA)
HDAC
histone deacetylase
vascular endothelial growth factor (VEGF)
Online Access:https://www.mdpi.com/2073-4409/10/4/878

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https://www.mdpi.com/2073-4409/10/4/878

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