Skeletal endocrinology: where evolutionary advantage meets disease

Abstract The regulation of whole-body homeostasis by the skeleton is mediated by its capacity to secrete endocrine signaling molecules. Although bone-derived hormones confer several adaptive benefits, their physiological functions also involve trade-offs, thus eventually contributing to disease. In...

Full description

Bibliographic Details
Main Authors: Nikolai Jaschke, Wolfgang Sipos, Lorenz C. Hofbauer, Tilman D. Rachner, Martina Rauner
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00149-x