Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes

Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes

The four dengue virus serotypes (DENV1 to 4) cause dengue, a major public health problem worldwide. Individuals exposed to primary DENV infections develop serotype-specific neutralizing antibodies, including strongly neutralizing antibodies targeting quaternary epitopes. To date, no studies have mea...

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Bibliographic Details
Main Authors: Daniela V. Andrade, Leah C. Katzelnick, Doug G. Widman, Angel Balmaseda, Aravinda M. de Silva, Ralph S. Baric, Eva Harris, Diane E. Griffin
Format: Article
Language:English
Published: American Society for Microbiology 2017-09-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/5/e01205-17

Internet

http://mbio.asm.org/cgi/content/full/8/5/e01205-17

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