The sustained and targeted treatment of hemangiomas by propranolol-loaded CD133 aptamers conjugated liposomes-in-microspheres

The sustained and targeted treatment of hemangiomas by propranolol-loaded CD133 aptamers conjugated liposomes-in-microspheres

We previously developed propranolol-encapsulated liposomes-in-microspheres (PLIM) to realize the sustained propranolol release for the treatment of hemangiomas. However, the liposomes released from the microspheres still lacked specificity for CD133-positive hemangioma-derived stem cells (HemSCs) wh...

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Bibliographic Details
Main Authors: Xiaonan Guo, Changxian Dong, Qiuyu Liu, Xiaoshuang Zhu, Song Zuo, Hongyu Zhang
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CD133
Hemangiomas
Propranolol
Liposomes
Microspheres
Sustained release
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219306535

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http://www.sciencedirect.com/science/article/pii/S0753332219306535

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