Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2−/− Lung Fibroblasts

The differential expression of two closelyassociated cyclooxygenase isozymes, COX-1 and COX-2, exhibited functions beyond eicosanoid metabolism. We hypothesized that COX-1 or COX-2 knockout lung fibroblasts may display altered protein profiles which may allow us to further differentiate the function...

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Bibliographic Details
Main Authors: Mandar Dave, Abul B.M.M.K. Islam, Roderick V. Jensen, Agueda Rostagno, Jorge Ghiso, Ashok R. Amin
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
MIF
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022917301729