Thrombospondin-1: A Key Protein That Induces Fibrosis in Diabetic Complications

Fibrosis accompanies most common pathophysiological features of diabetes complications in different organs. It is characterized by an excessive accumulation of extracellular matrix (ECM) components, the response to which contributes to inevitable organ injury. The extracellular protein thrombospondi...

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Bibliographic Details
Main Authors: Linhao Xu, Yong Zhang, Jian Chen, Yizhou Xu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2020/8043135