Lynch Syndrome: An Updated Review
Lynch syndrome is one of the most common cancer susceptibility syndromes. Individuals with Lynch syndrome have a 50%–70% lifetime risk of colorectal cancer, 40%–60% risk of endometrial cancer, and increased risks of several other malignancies. It is caused by germline mutations in the DNA mismatch...
Main Authors: | Rishabh Sehgal, Kieran Sheahan, Patrick R. O'Connell, Ann M. Hanly, Sean T. Martin, Desmond C. Winter |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-06-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/5/3/497 |
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