Metabolic features of cancer cells impact immunosurveillance

Metabolic features of cancer cells impact immunosurveillance

Background Tumors rewire their metabolism to achieve robust anabolism and resistance against therapeutic interventions like cisplatin treatment. For example, a prolonged exposure to cisplatin causes downregulation of pyridoxal kinase (PDXK), the enzyme that generates the active vitamin B6, and upreg...

Full description

Bibliographic Details
Main Authors: Christophe Klein, Diane Damotte, Adrien Joseph, Sebastien Gouy, Marco Alifano, Marie-Caroline Dieu-Nosjean, Guido Kroemer, Eric Deutsch, Antoine Lafarge, Philippe Morice, Julien Adam, Patricia Pautier, Cyrus Chargari, Isabelle Cremer, Catherine Genestie, Pan Juncheng, Michele Mondini, Nizar Labaied, Mauro Loi, Valentina Astesana, Florine Obrist, Norma Bloy, Gautier Stoll, Nicolas Signolle, Judith Michels, Maria Castedo
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/6/e002362.full

Internet

https://jitc.bmj.com/content/9/6/e002362.full

Similar Items