Effects of Camphorquinone on Cytotoxicity, Cell Cycle Regulation and Prostaglandin E2 Production of Dental Pulp Cells: Role of ROS, ATM/Chk2, MEK/ERK and Hemeoxygenase-1.

Camphorquinone (CQ) is a popularly-used photosensitizer in composite resin restoration. In this study, the effects of CQ on cytotoxicity and inflammation-related genes and proteins expression of pulp cells were investigated. The role of reactive oxygen species (ROS), ATM/Chk2/p53 and hemeoxygenase-1...

Full description

Bibliographic Details
Main Authors: Mei-Chi Chang, Li-Deh Lin, Min-Tsz Wu, Chiu-Po Chan, Hsiao-Hua Chang, Ming-Shu Lee, Tzu-Ying Sun, Po-Yuan Jeng, Sin-Yuet Yeung, Hsueh-Jen Lin, Jiiang-Huei Jeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4682794?pdf=render