Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

<p>Abstract</p> <p>Background</p> <p>Mutations in the presenilin (<it>PSEN</it>) genes are associated with early-onset familial Alzheimer's disease (FAD). Biochemical characterizations and comparisons have revealed that many PSEN mutations alter γ-secre...

Full description

Bibliographic Details
Main Authors: Kalback Walter M, Patton R Lyle, Kokjohn Tyler A, Vidal Ruben, Spina Salvatore, Daugs Ian D, Maarouf Chera L, Luehrs Dean C, Walker Douglas G, Castaño Eduardo M, Beach Thomas G, Ghetti Bernardino, Roher Alex E
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/3/1/20

Internet

http://www.molecularneurodegeneration.com/content/3/1/20

Similar Items