Anti-Inflammatory Properties of Sirtuin 6 in Human Umbilical Vein Endothelial Cells
A prominent feature of inflammatory diseases is endothelial dysfunction. Factors associated with endothelial dysfunction include proinflammatory cytokines, adhesion molecules, and matrix degrading enzymes. At the transcriptional level, they are regulated by the histone deacetylase sirtuin (SIRT) 1 v...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2012/597514 |