The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

<h4>Background</h4>MBD5 and MBD6 are two uncharacterized mammalian proteins that contain a putative Methyl-Binding Domain (MBD). In the proteins MBD1, MBD2, MBD4, and MeCP2, this domain allows the specific recognition of DNA containing methylated cytosine; as a consequence, the proteins...

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Bibliographic Details
Main Authors: Sophie Laget, Michael Joulie, Florent Le Masson, Nobuhiro Sasai, Elisabeth Christians, Sriharsa Pradhan, Richard J Roberts, Pierre-Antoine Defossez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20700456/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20700456/?tool=EBI

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