Infection by Anaplasma phagocytophilum Requires Recruitment of Low-Density Lipoprotein Cholesterol by Flotillins

Cholesterol is essential for animal cells, but most bacteria do not depend on cholesterol and instead lack cholesterol. However, the intracellular Gram-negative bacterium Anaplasma phagocytophilum that causes human granulocytic anaplasmosis (HGA) is unusual, as it contains significant amount of chol...

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Bibliographic Details
Main Authors: Qingming Xiong, Mingqun Lin, Weiyan Huang, Yasuko Rikihisa
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mBio
Subjects:
LDL
Online Access:https://doi.org/10.1128/mBio.02783-18