Isocorydine Derivatives and Their Anticancer Activities

Isocorydine Derivatives and Their Anticancer Activities

In order to improve the anticancer activity of isocorydine (ICD), ten isocorydine derivatives were prepared through chemical structure modifications, and their in vitro and in vivo activities were experimentally investigated. 8-Amino-isocorydine (8) and 6a,7-dihydrogen-isocorydione (10) could inhib...

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Bibliographic Details
Main Authors: Mei Zhong, Yanjuan Liu, Junxi Liu, Duolong Di, Mengrou Xu, Yaya Yang, Wenguang Li, Yali Chen, Jinxia Liu
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
aporphine alkaloids
isocorydine
synthesis
anticancer activity
Online Access:http://www.mdpi.com/1420-3049/19/8/12099

Internet

http://www.mdpi.com/1420-3049/19/8/12099

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