Coumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study

Objective(s): To investigate the efficiency of a novel series of coumarin derivatives bearing benzoheterocycle moiety as novel cholinesterase inhibitors. Materials and Methods: Different 7-hydroxycoumarin derivatives were synthesized via Pechmann or Knoevenagel condensation and conjugated to differe...

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Bibliographic Details
Main Authors: Kimia Hirbod, Leili Jalili-baleh, Hamid Nadri, Seyed Esmaeil Ebrahimi, Alireza Moradi, Bahar Pakseresht, Alireza Foroumadi, Abbas Shafiee, Mehdi Khoobi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_8830_b043e8e9f0c14364270454802e242e00.pdf