The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations

The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations

Here, we investigated how LDL receptor deficiency (Ldlr−/−) modulates the effects of testosterone on obesity and related metabolic dysfunctions. Though sham-operated Ldlr−/− mice fed Western-type diet for 12 weeks became obese and showed disturbed plasma glucose metabolism and plasma cholesterol and...

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Bibliographic Details
Main Authors: Caterina Constantinou, Diogenis Mpatsoulis, Anastasios Natsos, Peristera-Ioanna Petropoulou, Evangelia Zvintzou, Abdulmaged M. Traish, Peter J. Voshol, Iordanes Karagiannides, Kyriakos E. Kypreos
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Journal of Lipid Research
Subjects:
testosterone
metabolic syndrome
low density lipoprotein receptor-related protein 1
apolipoprotein E
diabetes
plasma glucose homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352494

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http://www.sciencedirect.com/science/article/pii/S0022227520352494

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